1. Hepatic anatomy and physiology – metabolic, synthetic, and excretory functions, dual blood supply and regulation, and evaluation of liver function tests.
2. Effects of anesthesia on hepatic function and the effect of hepatic failure on the pharmacokinetics and pharmacodynamics of anesthetic agents.
3. Pre-operative assessment of patients with hepatic dysfunction – central nervous system, respiratory, cardiovascular, hematologic, endocrine, renal, gastrointestinal, infectious, and nutritional issues.
4. Anesthetic considerations and management of patient with end-stage liver disease including cirrhosis, ascites, and portal hypertension.
5. Anesthetic considerations and management of patient for liver transplantation – pre-anhepatic, anhepatic, and neohepatic phases.
6. Reperfusion syndrome – pathophysiology, clinical manifestations, and management strategies.
7. Anesthetic considerations and management of patient with pulmonary hypertension and hepato-pulmonary syndrome.
8. Issues and management of coagulopathy and massive transfusions.
9. Anesthetic considerations and management of patient for living related liver donation.
10. Anesthetic considerations and management of patient for liver resection.
11. Anesthetic considerations and management of patient for transjugular intrahepatic portosystemic shunts (TIPS).